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Showing posts with the label Geriatrics

Tome Jones at 81, sings about aging on his new album

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NPR and Bob Boilen | June 7, 2021: "We're publishing this Tom Jones Tiny Desk (home) concert on his 81st birthday. It's a poignant moment in the life of a singer whose career spans 56 years and more than 100 million records sold; the passing of his wife, Linda, in 2016 after 59 years of marriage was devastating and resulted in the longest break between recordings of his career. But now Tom Jones is back with a new album, Surrounded By Time, and ready to share his deepest feelings, channeling songs by others with a voice still rich and muscular. The songs on the album (and for this Tiny Desk) deal so eloquently with time and aging. Tom Jones sings Bob Dylan's "One More Cup Of Coffee" and going "down to the valley below." Then, he takes on Malvina Reynolds' folk tune "There's No Hole In My Head" and turns it into a fierce statement about being yourself. When Tom Jones was 33, and after one of his infamous shows in Las Vegas, jazz com...

Senolytic drugs target senescent cells (known as "zombie cells"), hoping to delay aging

Clinical geriatrician Dr James Kirkland, Director of the Robert and Arlene Kogod Center on Aging at Mayo Clinic, said: “Most people don’t want to live to 130 and feel like they’re 130 but they wouldn’t mind living to 90 or 100 and feel like they’re 60. And now that can actually be achieved in animals. You tend to find older individuals who are completely healthy and are playing 18 rounds of golf a day, or they’ve got three, five or 10 different conditions. There aren’t too many people in between. If you get one age-related disease, you’ve got a huge chance of having several." Read more here: https://uk.news.yahoo.com/wonder-drugs-target-apos-zombie-190000268.html

Lifespan vs. healthspan: "I'LL do it" mnemonic

Epigenetics "Tthere is nobody who disputes that epigenetics predicts life span”. Aging eight or more years faster than your calendar age equates to twice the typical risk of dying, while aging seven years slower is associated with half the risk of death, Horvath says. "Life span predictor" clock His lab has developed a "life span predictor" they named it after the Grim Reaper: DNAm GrimAge. The epigenetic clock is more accurate the younger a person is. It’s especially inaccurate for the very old. “At this point, we don’t have any evidence that it’s clinically useful, because there are big error bars.” Seed of the clock is strongly influenced by underlying genes: 40% of the ticking rate is determined by genetic inheritance, and the rest by lifestyle and luck: " I'LL do it" mnemonic: I nheritance L ifestyle L uck Eating a healthy diet including lots of vegetables and fish is associated with slower epigenetic aging. Sleep deprication speeds the cloc...

The key to successful ageing is to be a master of 3 domains: physical health, mental wellbeing, and social connectedness

From The Lancet: Life expectancy in the UK continues to increase by 2 years per decade. Unfortunately, these extra years do not seem to be spent in better health, with morbidity and dependency increasing over the past 20 years. So what can be done to develop resilience with increasing age? Seize control of your health and be better prepared—physically, mentally, and socially—for our later years. This a recurring theme covering 3 domains: physical, mental and social. The Lancet reviewed the book Enlightened Aging: Building Resilience for a Long, Active Life , by Eric B Larson and Joan DeClaire. One of the most memorable vignette from the book was of Evangeline Shuler, a centenarian, with a “glass half full” approach to life: as she grew older and her friends died, her attitude was to go out and “make new ones”; an avid reader, as she became blind, she switched to audio books. Translating scientific facts into practical strategies early in the life course can help us live better for lon...

BMJ study: Patients treated by older physicians (60 and older) had higher mortality vs. younger physicians (39 and younger)

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From BMJ: The researchers evaluated a 20% random sample of Medicare fee-for-service beneficiaries aged 65 and older admitted to hospital with a medical condition in 2011-14 and treated by hospitalist physicians. Main outcome measures 30 day mortality and readmissions and costs of care. The study included 700,000 admissions managed by 18,800 hospitalist physicians (median age 41). Patients’ adjusted 30 day mortality rates were: - 10.8% for physicians younger than 40 - 11.1% for physicians aged 40-49 - 11.3% for physicians aged 50-59 - 12.1% for physicians aged 60 and older See the figure here: http://www.bmj.com/content/bmj/357/bmj.j1797/F1.large.jpg Note: Among physicians with a high volume of patients, however, there was no association between physician age and patient mortality. Within the same hospital, patients treated by older physicians had higher mortality than patients cared for by younger physicians, except those physicians treating high volumes of patients. The calculated ...

"Bodies have a way of not keeping up with your brain or your career" - Glover from Deep Purple on approaching retirement

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Roger Glover from Deep Purple: "We're all about late 60s, early 70s, and bodies have a way of not keeping up with your brain or your career. The time is approaching when it will end, but we don't want to face that. We don't actually want to make a date or a final tour or anything. We just want to carry on as long as nature allows or is kind of dignified. If we can't do what we do anymore, then yes, it's time to stop. But we're still doing it, and we're still enjoying it very much. So all we're saying is the door is closing, but it's not closed yet." Glover and Paice's Rock Antenne interview: References: Hamburg http://buff.ly/2luoS1E Photo Shoot for Deep Purple's 'Infinite': Exclusive Behind-the-Scenes Footage http://buff.ly/2mbtyxv

Drummer Leonard Haze's thoughts on old age and dying

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Leonard Haze was a great drummer. He passed away in his sleep last weekend at age 61. I saw him on tour with Ian Gillan in 1992 and the whole band was amazing. He had this humongous Ludwig drum kit and was a powerful drummer. Lenny Haze recorded the Toolbox album with Gillan, one of the songs from the album, Don't hold me back, is linked below: Considering the recent deaths of many rock and roll greats, this Facebook post by Lenny from January seems very relevant: Leonard Haze, thinking about a lot of things . January 2: "That's enough. Why is it so hard to get old ? You loose friends as you go. With Bill F rates today that's for me since Christmas a total of 4 people I know passing away. Christmas eve my step daughter Danielle Galvin ' s Aunt & best friend at 36. From something she didn't know about. Lemmy two days after Christmas something he just discovered. Bill Frates today. I heard he was very I'll but still. You add on Mark Weaver & I am sorr...